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 B  AB  JB*  OB  OE*  OE
 S  AS  JS*  OS  OS*  3
 JB
 JS
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Detailed Insider History for:
PRAXIS PRECISION MEDICINES INC: PRAX
Price: 1/16/26 52-Wk
High		 52-Wk
Low		 Mkt Cap (mm) Shrs Out (mm) 3-Mth Ave
Vol (m)		 Ind. Yield Short Int
% Float		 Inst. Owned Insider Owned
$314.04 $326.91 $26.70 $8,711 28 908 0.0% 15.0% 87.80% 0.24%
Exch Sector Industry Sub-Industry
NasdaqGS Manufacturing Chemicals And Allied Products Pharmaceutical Preparations
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Insider Statistics
T N H M S
Filer Name
Insider Title
Trans Type
Dollar Value
Shares Traded
Trans Date From
Trans Date To
Trans Price From
Trans Price To
Total Holdings
Delta % Owned
Owned
Other Info
Input Date
1
    
 
MASTROCOLA LAUREN
AO
JS
$94,855
344
---
1/12/26
---
$275.74
13,446
-2.5
D
R
1/13/26 - 8:20:33 pm
2
    
 
SNIECINSKI MEGAN
COO
JS
$244,030
885
---
1/12/26
---
$275.74
28,530
-3.0
D
R
1/13/26 - 8:19:50 pm
3
    
 
NEMIROFF ALEX
GC,SEC
JS
$211,768
768
---
1/12/26
---
$275.74
25,933
-2.9
D
R
1/13/26 - 8:19:19 pm
4
    
 
KELLY TIMOTHY EDWIN
CFO
JS
$260,023
943
---
1/12/26
---
$275.74
31,046
-2.9
D
R
1/13/26 - 8:18:33 pm
5
    
 
MASTROCOLA LAUREN
AO
JS
$105,861
367
---
1/10/26
---
$288.45
13,790
-2.6
D
R
1/12/26 - 5:51:02 pm
6
    
 
SNIECINSKI MEGAN
COO
JS
$313,545
1,087
---
1/10/26
---
$288.45
29,415
-3.6
D
R
1/12/26 - 5:50:29 pm
7
    
 
NEMIROFF ALEX
GC,SEC
JS
$264,509
917
---
1/10/26
---
$288.45
26,701
-3.3
D
R
1/12/26 - 5:49:56 pm
8
    
 
KELLY TIMOTHY EDWIN
CFO
JS
$385,081
1,335
---
1/10/26
---
$288.45
31,989
-4.0
D
R
1/12/26 - 5:49:02 pm
9
    
 
SOUZA MARCIO
CEO,DIR
JS
$1,226,489
4,252
---
1/10/26
---
$288.45
76,890
-5.2
D
R
1/12/26 - 5:48:23 pm
10
    
 
MASTROCOLA LAUREN
AO
JB
---
3,750
---
1/8/26
---
---
14,157
36.0
D
R
1/12/26 - 5:51:02 pm
11
    
 
SNIECINSKI MEGAN
COO
JB
---
9,625
---
1/8/26
---
---
30,502
46.1
D
R
1/12/26 - 5:50:29 pm
12
    
 
NEMIROFF ALEX
GC,SEC
JB
---
6,875
---
1/8/26
---
---
27,618
33.1
D
R
1/12/26 - 5:49:56 pm
13
    
 
KELLY TIMOTHY EDWIN
CFO
JB
---
8,800
---
1/8/26
---
---
33,324
35.9
D
R
1/12/26 - 5:49:02 pm
14
    
 
SOUZA MARCIO
CEO,DIR
JB
---
27,640
---
1/8/26
---
---
81,142
51.7
D
R
1/12/26 - 5:48:23 pm
15
    
 
ARBUCKLE STUART A
DIR
3
---
---
---
1/8/26
---
---
---
---
---
---
1/12/26 - 5:46:56 pm
16
    
 
KINDLER JEFFREY B
DIR
3
---
---
---
1/8/26
---
---
---
---
---
---
1/12/26 - 5:44:39 pm
17
    
 
MASTROCOLA LAUREN
AO
JS
$10,242
35
---
1/7/26
---
$292.63
10,407
-0.3
D
R
1/9/26 - 4:47:53 pm
18
    
 
NEMIROFF ALEX
GC,SEC
JS
$26,044
89
---
1/7/26
---
$292.63
20,743
-0.4
D
R
1/9/26 - 4:47:25 pm
19
    
 
KELLY TIMOTHY EDWIN
CFO
JS
$40,676
139
---
1/7/26
---
$292.63
24,524
-0.6
D
R
1/9/26 - 4:47:02 pm
20
    
 
SOUZA MARCIO
CEO,DIR
JS
$118,515
405
---
1/7/26
---
$292.63
53,502
-0.8
D
R
1/9/26 - 4:46:36 pm
21
    
 
SNIECINSKI MEGAN
COO
3
---
---
---
1/1/26
---
---
20,877
---
D
R
1/9/26 - 4:37:04 pm
22
    
 
SOUZA MARCIO
CEO,DIR
JS
---
400
---
12/30/25
---
---
2,600
-13.3
I
---
12/31/25 - 7:17:43 pm
23
    
 
NEMIROFF ALEX
GC,SEC
OS
$4,852,256
25,130
---
11/20/25
$190.86
$194.30
20,832
-54.7
D
---
11/21/25 - 9:41:39 pm
24
    
 
NEMIROFF ALEX
GC,SEC
OE
$1,853,531
25,130
---
11/20/25
$44.40
$56.94
45,962
120.6
D
---
11/21/25 - 9:41:39 pm
25
    
 
MASTROCOLA LAUREN
AO
OS
$2,612,244
13,600
---
11/20/25
$191.96
$192.71
10,442
-56.6
D
---
11/21/25 - 9:39:47 pm
26
    
 
MASTROCOLA LAUREN
AO
OE
$831,257
13,600
---
11/20/25
$43.37
$56.94
24,042
130.2
D
---
11/21/25 - 9:39:47 pm
27
    
 
KELLY TIMOTHY EDWIN
CFO
JB
$12,142
384
---
11/14/25
---
$31.62
24,663
1.6
D
---
11/21/25 - 9:42:37 pm
28
    
 
ADAGE CAPITAL MANAGEMENT L P
BO
JS
$33,198,124
313,910
---
10/16/25
$90.00
$140.00
2,060,175
-13.2
I
---
10/17/25 - 4:10:45 pm
29
1y
2
50%
3,217%
6
MITCHELL DEAN J
DIR
OB
$483,991
12,251
---
9/24/25
$14.36
$44.04
17,251
245.0
D
---
9/25/25 - 4:40:48 pm
30
    
 
ADAGE CAPITAL MANAGEMENT L P
BO
3
---
---
---
8/18/25
---
---
2,374,085
---
I
---
8/19/25 - 4:10:13 pm
31
    
 
SOUZA MARCIO
CEO,DIR
JB
$10,974
348
---
5/14/25
---
$31.54
53,907
0.6
D
---
5/19/25 - 4:57:11 pm
32
    
 
KELLY TIMOTHY EDWIN
CFO
JB
$7,852
249
---
5/14/25
---
$31.54
24,279
1.0
D
---
5/19/25 - 4:55:38 pm
33
    
 
NEMIROFF ALEX
GC,SEC
JS
$4,355
51
---
2/12/25
---
$85.40
20,832
-0.2
D
R
2/14/25 - 4:29:47 pm
34
    
 
MASTROCOLA LAUREN
AO
JS
$3,416
40
---
2/12/25
---
$85.40
10,442
-0.4
D
R
2/14/25 - 4:29:37 pm
35
    
 
SOUZA MARCIO
CEO,DIR
JS
$34,245
401
---
2/12/25
---
$85.40
53,559
-0.7
D
R
2/14/25 - 4:29:25 pm
36
    
 
MASTROCOLA LAUREN
AO
JS
$24,629
390
---
1/12/25
---
$63.15
10,482
-3.6
D
R
1/14/25 - 6:51:07 pm
37
    
 
KELLY TIMOTHY EDWIN
CFO
JS
$42,689
676
---
1/12/25
---
$63.15
24,030
-2.7
D
R
1/14/25 - 6:50:47 pm
38
    
 
NEMIROFF ALEX
GC,SEC
JS
$36,564
579
---
1/12/25
---
$63.15
20,883
-2.7
D
R
1/14/25 - 6:50:35 pm
39
    
 
MASTROCOLA LAUREN
AO
JB
---
5,000
---
1/10/25
---
---
10,872
85.2
D
R
1/14/25 - 6:51:07 pm
40
    
 
SOUZA MARCIO
CEO,DIR
JB
---
37,500
---
1/10/25
---
---
53,960
227.8
D
R
1/14/25 - 6:50:56 pm
41
    
 
KELLY TIMOTHY EDWIN
CFO
JB
---
12,500
---
1/10/25
---
---
24,706
102.4
D
R
1/14/25 - 6:50:47 pm
42
    
 
NEMIROFF ALEX
GC,SEC
JB
---
11,250
---
1/10/25
---
---
21,462
110.2
D
R
1/14/25 - 6:50:35 pm
43
    
 
SOUZA MARCIO
CEO,DIR
JS
$33,644
434
---
1/7/25
---
$77.52
16,460
-2.6
D
R
1/8/25 - 7:50:35 pm
44
    
 
MASTROCOLA LAUREN
AO
JS
$2,713
35
---
1/7/25
---
$77.52
5,872
-0.6
D
R
1/8/25 - 7:50:24 pm
45
    
 
NEMIROFF ALEX
GC,SEC
JS
$6,899
89
---
1/7/25
---
$77.52
10,212
-0.9
D
R
1/8/25 - 7:50:14 pm
46
    
 
KELLY TIMOTHY EDWIN
CFO
JS
$10,775
139
---
1/7/25
---
$77.52
12,206
-1.1
D
R
1/8/25 - 7:50:02 pm
47
    
 
MASTROCOLA LAUREN
AO
JB
$10,996
294
---
11/14/24
---
$37.40
5,907
5.2
D
---
11/19/24 - 9:50:17 pm
48
    
 
KELLY TIMOTHY EDWIN
CFO
JB
$7,667
205
---
11/14/24
---
$37.40
12,345
1.7
D
---
11/19/24 - 9:48:39 pm
49
    
 
NEMIROFF ALEX
GC,SEC
OS
$660,827
8,239
---
11/14/24
---
$80.20
10,301
-44.4
D
---
11/15/24 - 9:30:49 pm
50
    
 
NEMIROFF ALEX
GC,SEC
OE
$431,776
7,583
---
11/14/24
---
$56.94
18,540
69.2
D
---
11/15/24 - 9:30:49 pm
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