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 B  AB  JB*  OB  OE*  OE
 S  AS  JS*  OS  OS*  3
 JB
 JS
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Detailed Insider History for:
IONIS PHARMACEUTICALS INC: IONS
Price: 10/31/25 52-Wk
High		 52-Wk
Low		 Mkt Cap (mm) Shrs Out (mm) 3-Mth Ave
Vol (m)		 Ind. Yield Short Int
% Float		 Inst. Owned Insider Owned
$74.30 $75.49 $23.95 $12,035 162 2,483 0.0% 11.4% 106.95% 0.63%
Exch Sector Industry Sub-Industry
NasdaqGS Manufacturing Chemicals And Allied Products Pharmaceutical Preparations
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Insider Statistics
T N H M S
Filer Name
Insider Title
Trans Type
Dollar Value
Shares Traded
Trans Date From
Trans Date To
Trans Price From
Trans Price To
Total Holdings
Delta % Owned
Owned
Other Info
Input Date
1
    
 
SWAYZE ERIC
VP
S
$3,902
53
---
10/16/25
---
$73.62
256
-17.2
I
R
10/16/25 - 8:16:46 pm
2
    
 
DEVERS SHANNON L
VP,HR
OS
$530,638
7,263
10/15/25
10/16/25
$72.94
$73.62
15,937
-31.3
D
R,10b
10/16/25 - 8:16:08 pm
3
    
 
SWAYZE ERIC
VP
JB
---
125
---
10/15/25
---
---
309
67.9
I
R
10/16/25 - 8:16:46 pm
4
1y
23
70%
-34%
3
PARSHALL B LYNNE
DIR
AS
$358,722
5,000
---
10/15/25
---
$71.74
61,344
-7.5
D
10b
10/16/25 - 8:16:14 pm
5
    
 
DEVERS SHANNON L
VP,HR
JB
---
2,820
---
10/15/25
---
---
18,757
17.7
D
R,10b
10/16/25 - 8:16:08 pm
6
    
 
DEVERS SHANNON L
VP,HR
OE
$291,060
6,000
---
10/15/25
---
$48.51
21,937
37.6
D
R,10b
10/16/25 - 8:16:08 pm
7
    
 
BIRCHLER BRIAN
VP,OO
OS
$1,723,987
23,900
10/14/25
10/15/25
$72.03
$72.23
56,826
-29.6
D
10b
10/16/25 - 8:15:51 pm
8
    
 
BIRCHLER BRIAN
VP,OO
OE
$1,285,103
23,900
10/14/25
10/15/25
---
$53.77
69,251
52.7
D
10b
10/16/25 - 8:15:51 pm
9
    
 
SWAYZE ERIC
VP
AS
$472,718
6,849
---
10/6/25
---
$69.02
30,453
-18.4
D
10b
10/8/25 - 6:37:06 pm
10
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$937,338
13,441
---
10/6/25
---
$69.27
53,889
-20.0
D
10b
10/8/25 - 6:37:00 pm
11
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$539,274
10,200
---
10/6/25
---
$52.87
67,330
17.9
D
10b
10/8/25 - 6:37:00 pm
12
1y
32
75%
-41%
1
MONIA BRETT P
CEO,DIR
AS
$30,268
437
---
10/6/25
---
$69.26
179,572
-0.2
D
10b
10/8/25 - 6:36:54 pm
13
    
 
BAROLDI JOSEPH
VP
AS
$112,725
1,625
---
10/6/25
---
$69.37
30,301
-5.1
D
10b
10/8/25 - 6:36:47 pm
14
    
 
SWAYZE ERIC
VP
OS
$1,793,744
27,114
10/1/25
10/2/25
$66.09
$66.23
37,302
-42.1
D
10b
10/2/25 - 7:36:11 pm
15
    
 
SWAYZE ERIC
VP
OE
$1,457,920
27,114
10/1/25
10/2/25
---
$53.77
51,444
111.4
D
10b
10/2/25 - 7:36:11 pm
16
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$4,377,055
64,664
---
10/2/25
---
$67.69
57,130
-53.1
D
10b
10/2/25 - 7:35:57 pm
17
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$3,813,257
64,664
---
10/2/25
$56.78
$60.89
91,591
240.1
D
10b
10/2/25 - 7:35:57 pm
18
    
 
BAROLDI JOSEPH
VP
OS
$1,020,210
15,000
---
10/2/25
---
$68.01
31,926
-32.0
D
10b
10/2/25 - 7:35:51 pm
19
    
 
BAROLDI JOSEPH
VP
OE
$477,000
15,000
---
10/2/25
---
$31.80
46,926
47.0
D
10b
10/2/25 - 7:35:51 pm
20
1y
2
50%
3%
1
WENDER JOSEPH H
DIR
AS
$1,100,385
16,800
---
10/1/25
---
$65.50
92,035
-15.4
I
10b
10/2/25 - 7:36:16 pm
21
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$1,634,922
25,300
9/29/25
9/30/25
$64.54
$64.68
57,130
-30.7
D
10b
10/1/25 - 4:55:36 pm
22
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$1,436,534
25,300
9/29/25
9/30/25
---
$56.78
71,957
54.2
D
10b
10/1/25 - 4:55:36 pm
23
1y
24
92%
-69%
1
GEARY RICHARD S
VP
OS
$3,777,668
57,900
---
9/30/25
---
$65.24
79,657
-42.1
D
10b
10/1/25 - 4:55:29 pm
24
    
 
GEARY RICHARD S
VP
OE
$3,113,283
57,900
---
9/30/25
---
$53.77
137,557
72.7
D
10b
10/1/25 - 4:55:29 pm
25
1y
22
73%
-51%
1
HOUGEN ELIZABETH L
VP,CFO
OS
$3,249,734
49,800
---
9/30/25
---
$65.26
110,500
-31.1
D
10b
10/1/25 - 4:55:20 pm
26
    
 
HOUGEN ELIZABETH L
VP,CFO
OE
$2,677,746
49,800
---
9/30/25
---
$53.77
160,300
45.1
D
10b
10/1/25 - 4:55:20 pm
27
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$109,787
1,700
---
9/12/25
---
$64.58
57,130
-2.9
D
10b
9/16/25 - 4:56:38 pm
28
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$96,526
1,700
---
9/12/25
---
$56.78
58,830
3.0
D
10b
9/16/25 - 4:56:38 pm
29
    
 
BAROLDI JOSEPH
VP
OS
$742,838
11,950
---
9/9/25
---
$62.16
31,926
-27.2
D
10b
9/11/25 - 5:05:07 pm
30
    
 
BAROLDI JOSEPH
VP
OE
$380,010
11,950
---
9/9/25
---
$31.80
43,876
37.4
D
10b
9/11/25 - 5:05:07 pm
31
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$1,355,661
21,000
---
9/9/25
---
$64.56
57,130
-26.9
D
10b
9/11/25 - 5:04:46 pm
32
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$1,274,580
21,000
---
9/9/25
---
$56.78
77,130
37.4
D
10b
9/11/25 - 5:04:46 pm
33
    
 
BAROLDI JOSEPH
VP
OS
$15,500
250
---
9/5/25
---
$62.00
31,926
-0.8
D
10b
9/9/25 - 6:30:41 pm
34
    
 
BAROLDI JOSEPH
VP
OE
$7,950
250
---
9/5/25
---
$31.80
32,176
0.8
D
10b
9/9/25 - 6:30:41 pm
35
1y
29
48%
-12%
1
BENNETT C FRANK
VP
AS
$357,581
6,000
---
9/5/25
---
$59.60
82,679
-6.8
D
10b
9/9/25 - 6:30:25 pm
36
1y
2
50%
3%
1
WENDER JOSEPH H
DIR
AS
$1,612,156
28,000
9/2/25
9/3/25
$55.04
$60.14
108,835
-20.5
I
10b
9/4/25 - 8:40:10 pm
37
1y
32
75%
-41%
1
MONIA BRETT P
CEO,DIR
OS
$12,294,703
203,814
---
9/3/25
$59.12
$61.06
180,009
-53.1
D
10b
9/4/25 - 8:38:20 pm
38
    
 
MONIA BRETT P
CEO,DIR
OE
$9,032,039
203,814
---
9/3/25
---
$32.60
308,324
195.0
D
10b
9/4/25 - 8:38:20 pm
39
1y
25
72%
-33%
8
KLEIN JOSEPH III
DIR
AS
$1,680,000
28,000
---
9/3/25
---
$60.00
---
All
I
10b
9/4/25 - 8:38:01 pm
40
    
 
KLEIN JOSEPH III
DIR
JB
---
28,000
---
9/3/25
---
---
28,000
New
I
10b
9/4/25 - 8:38:01 pm
41
1y
25
72%
-33%
8
KLEIN JOSEPH III
DIR
AS
$1,680,000
28,000
---
9/3/25
---
$60.00
---
All
I
10b
9/4/25 - 8:37:27 pm
42
    
 
KLEIN JOSEPH III
DIR
JB
---
28,000
---
9/3/25
---
---
28,000
New
I
10b
9/4/25 - 8:37:27 pm
43
    
 
DEVERS SHANNON L
VP,HR
OS
$192,943
3,162
---
9/3/25
---
$61.02
15,009
-17.4
D
10b
9/4/25 - 8:36:34 pm
44
    
 
DEVERS SHANNON L
VP,HR
OE
$114,207
3,162
---
9/3/25
---
$32.60
18,171
21.1
D
10b
9/4/25 - 8:36:34 pm
45
1y
2
50%
3%
1
WENDER JOSEPH H
DIR
AS
$1,612,156
28,000
9/2/25
9/3/25
$55.04
$60.14
108,835
-20.5
I
10b
9/4/25 - 8:34:45 pm
46
    
 
BAROLDI JOSEPH
VP
OS
$1,946,220
32,800
---
9/3/25
---
$59.09
16,926
-66.0
D
10b
9/4/25 - 8:34:11 pm
47
    
 
BAROLDI JOSEPH
VP
OE
$1,043,040
32,800
---
9/3/25
---
$31.80
46,926
232.2
D
10b
9/4/25 - 8:34:11 pm
48
1y
38
84%
-62%
1
O NEIL PATRICK R
VP,LO,GC
OS
$5,396,844
89,900
9/2/25
9/3/25
$54.51
$61.42
5,655
-94.1
D
10b
9/4/25 - 8:29:09 pm
49
    
 
O NEIL PATRICK R
VP,LO,GC
OE
$4,054,726
89,900
9/2/25
9/3/25
$32.60
$53.77
71,130
---
D
10b
9/4/25 - 8:29:09 pm
50
1y
29
48%
-12%
1
BENNETT C FRANK
VP
OS
$2,301,264
38,909
9/2/25
9/3/25
$49.14
$60.62
88,679
-30.5
D
10b
9/4/25 - 8:29:05 pm
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