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 has been a registered insider since 2003.
                                      
                                  As a Secretary at Denali Therapeutics,  last made a transaction on 8/12/2025.
                              
| 
                              InsiderInsights.com Purchase Scorecard
                             | 
|  |  | 
                              Transaction Date
                             | 
| Nq | Hit Rate
 | Mean Return
 | Median Return
 | Range of Returns
 | Time From Purchases
 | Nq | Hit Rate
 | Mean Return
 | Median Return
 | Range of Returns
 | 
| 7 | 43% | 5% | -27% | 202 | 1 Year | 7 | 0% | -- | -- | -- | 
| 9 | 44% | -2% | -7% | 118 | 9 Month | 9 | 0% | -- | -- | -- | 
| 9 | 44% | -7% | -22% | 87 | 6 Month | 9 | 0% | -- | -- | -- | 
| 9 | 33% | -2% | -9% | 92 | 3 Month | 9 | 0% | -- | -- | -- | 
| 9 | 44% | -5% | -8% | 39 | 1 Month | 9 | 0% | -- | -- | -- | 
| 9 | 11% | -7% | -5% | 24 | 1 Week | 9 | 0% | -- | -- | -- | 
| 
                              InsiderInsights.com Sales Scorecard
                             | 
|  |  | 
                              Transaction Date
                             | 
| Nq | Hit Rate
 | Mean Return
 | Median Return
 | Range of Returns
 | Time From Sales
 | Nq | Hit Rate
 | Mean Return
 | Median Return
 | Range of Returns
 | 
| 46 | 70% | 6% | -29% | 365 | 1 Year | 46 | 0% | -- | -- | -- | 
| 48 | 81% | -5% | -25% | 494 | 9 Month | 48 | 0% | -- | -- | -- | 
| 48 | 75% | -10% | -12% | 182 | 6 Month | 48 | 0% | -- | -- | -- | 
| 48 | 71% | -9% | -14% | 97 | 3 Month | 48 | 0% | -- | -- | -- | 
| 49 | 57% | -1% | -3% | 61 | 1 Month | 49 | 0% | -- | -- | -- | 
| 49 | 49% | -1% | 0% | 35 | 1 Week | 49 | 0% | -- | -- | -- | 
| Scorecards Updated 10/29/2025 02:29 AM EST | Latest Transaction Date: | 8/12/2025 | 
| Average days between Transaction and Entered Dates: | 3 |