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 B  AB  JB*  OB  OE*  OE
 S  AS  JS*  OS  OS*  3
 JB
 JS
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Detailed Insider History for:
IONIS PHARMACEUTICALS INC: IONS
Price: 1/30/26 52-Wk
High		 52-Wk
Low		 Mkt Cap (mm) Shrs Out (mm) 3-Mth Ave
Vol (m)		 Ind. Yield Short Int
% Float		 Inst. Owned Insider Owned
$82.67 $86.15 $23.95 $13,390 162 2,458 0.0% 11.2% 109.28% 0.63%
Exch Sector Industry Sub-Industry
NasdaqGS Manufacturing Chemicals And Allied Products Pharmaceutical Preparations
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#
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Insider Statistics
T N H M S
Filer Name
Insider Title
Trans Type
Dollar Value
Shares Traded
Trans Date From
Trans Date To
Trans Price From
Trans Price To
Total Holdings
Delta % Owned
Owned
Other Info
Input Date
1
1y
30
47%
-7%
1
BENNETT C FRANK
VP
OS
$792,797
12,891
---
9/3/25
---
$61.50
88,679
-12.7
D
10b
9/4/25 - 8:29:05 pm
2
1y
30
47%
-7%
1
BENNETT C FRANK
VP
OS
$2,301,264
38,909
9/2/25
9/3/25
$49.14
$60.62
88,679
-30.5
D
10b
9/4/25 - 8:29:05 pm
3
    
 
BENNETT C FRANK
VP
OE
$2,516,436
46,800
---
9/3/25
---
$53.77
135,479
52.8
D
10b
9/4/25 - 8:29:05 pm
4
1y
1
0%
92%
2
LOSCALZO JOSEPH
DIR
OS
$962,371
16,000
---
9/3/25
---
$60.15
36,330
-30.6
D
10b
9/4/25 - 8:28:42 pm
5
    
 
LOSCALZO JOSEPH
DIR
OE
$390,720
16,000
---
9/3/25
---
$24.42
52,330
44.0
D
10b
9/4/25 - 8:28:42 pm
6
    
 
SCHNEIDER EUGENE
VP
OS
$1,195,421
19,658
---
9/3/25
$60.46
$61.42
51,507
-27.6
D
10b
9/4/25 - 8:28:07 pm
7
    
 
SCHNEIDER EUGENE
VP
OE
$1,057,011
19,658
---
9/3/25
---
$53.77
71,165
38.2
D
10b
9/4/25 - 8:28:07 pm
8
    
 
SWAYZE ERIC
VP
AS
$552,862
11,130
---
9/2/25
$49.22
$53.68
37,302
-23.0
D
10b
9/4/25 - 8:41:06 pm
9
1y
23
70%
-34%
3
PARSHALL B LYNNE
DIR
AS
$1,018,298
20,000
---
9/2/25
$50.42
$51.49
66,344
-23.2
D
10b
9/4/25 - 8:38:48 pm
10
1y
25
88%
-63%
1
GEARY RICHARD S
VP
AS
$503,671
10,000
---
9/2/25
---
$50.37
79,657
-11.2
D
10b
9/4/25 - 8:37:01 pm
11
    
 
O NEIL PATRICK R
VP,LO,GC
JB
$9,172
331
---
8/29/25
---
$27.71
57,130
0.6
D
---
9/3/25 - 6:37:53 pm
12
    
 
MONIA BRETT P
CEO,DIR
JB
$5,237
189
---
8/29/25
---
$27.71
180,009
0.1
D
---
9/3/25 - 6:30:26 pm
13
    
 
GEARY RICHARD S
VP
JB
$4,572
165
---
8/29/25
---
$27.71
89,657
0.2
D
---
9/3/25 - 6:30:10 pm
14
    
 
BENNETT C FRANK
VP
JB
$5,902
213
---
8/29/25
---
$27.71
93,679
0.2
D
---
9/3/25 - 6:29:50 pm
15
    
 
BIRCHLER BRIAN
VP,OO
JB
$4,600
166
---
8/29/25
---
$27.71
56,826
0.3
D
---
9/3/25 - 6:26:34 pm
16
    
 
DIAZ ALLENE M
DIR
AS
$60,687
1,427
---
8/22/25
---
$42.53
18,368
-7.2
D
10b
8/26/25 - 5:23:52 pm
17
1y
30
47%
-7%
1
BENNETT C FRANK
VP
OS
$439,776
10,000
---
8/18/25
---
$43.98
93,466
-9.7
D
10b
8/20/25 - 6:14:40 pm
18
    
 
BENNETT C FRANK
VP
OE
$326,000
10,000
---
8/18/25
---
$32.60
103,466
10.7
D
10b
8/20/25 - 6:14:40 pm
19
1y
23
70%
-34%
3
PARSHALL B LYNNE
DIR
AS
$209,646
5,000
---
8/6/25
$41.87
$42.63
86,344
-5.5
D
10b
8/8/25 - 6:55:59 pm
20
1y
25
88%
-63%
1
GEARY RICHARD S
VP
AS
$428,593
10,000
---
8/5/25
---
$42.86
89,492
-10.1
D
10b
8/6/25 - 6:44:16 pm
21
    
 
SCHNEIDER EUGENE
VP
AS
$408,701
9,549
---
8/4/25
---
$42.80
51,507
-15.6
D
10b
8/5/25 - 5:28:00 pm
22
1y
34
71%
-33%
1
MONIA BRETT P
CEO,DIR
OS
$109,440
2,432
---
7/30/25
---
$45.00
179,820
-1.3
D
10b
8/1/25 - 4:06:41 pm
23
    
 
MONIA BRETT P
CEO,DIR
OE
$79,283
2,432
---
7/30/25
---
$32.60
182,252
1.4
D
10b
8/1/25 - 4:06:41 pm
24
    
 
LOSCALZO JOSEPH
DIR
JB
---
4,079
---
7/15/25
---
---
36,330
12.6
D
R
7/17/25 - 4:59:28 pm
25
    
 
YANG MICHAEL J
DIR
JB
---
4,079
---
7/15/25
---
---
6,010
211.2
D
R
7/17/25 - 4:54:38 pm
26
    
 
WENDER JOSEPH H
DIR
JB
---
4,079
---
7/15/25
---
---
136,835
3.1
I
R
7/17/25 - 4:54:31 pm
27
    
 
PARSHALL B LYNNE
DIR
JB
---
4,079
---
7/15/25
---
---
91,344
4.7
D
R
7/17/25 - 4:54:25 pm
28
    
 
HERMAN JOAN E
DIR
JB
---
4,079
---
7/15/25
---
---
46,086
9.7
D
R
7/17/25 - 4:54:08 pm
29
    
 
HAYDEN MICHAEL R
DIR
JB
---
4,079
---
7/15/25
---
---
54,298
8.1
D
R
7/17/25 - 4:54:01 pm
30
    
 
DIAZ ALLENE M
DIR
JB
---
4,079
---
7/15/25
---
---
19,795
26.0
D
R
7/17/25 - 4:53:54 pm
31
    
 
BERTHELSEN SPENCER R
DIR
JB
---
4,079
---
7/15/25
---
---
156,013
2.7
D
R
7/17/25 - 4:53:48 pm
32
1y
34
71%
-33%
1
MONIA BRETT P
CEO,DIR
AS
$48,416
1,160
---
7/11/25
---
$41.74
179,820
-0.6
D
10b
7/15/25 - 8:54:09 pm
33
1y
1
100%
120%
5
HAYDEN MICHAEL R
DIR
B
$477,900
15,000
---
5/1/25
---
$31.86
50,219
42.6
D
---
5/2/25 - 4:38:26 pm
34
    
 
BIRCHLER BRIAN
VP,OO
S
$19,292
680
---
4/16/25
---
$28.37
56,660
-1.2
D
R
4/17/25 - 4:53:27 pm
35
    
 
JENNE KYLE
VP
S
$85,534
3,016
---
4/16/25
---
$28.36
11,199
-21.2
D
R
4/17/25 - 4:53:18 pm
36
    
 
BAROLDI JOSEPH
VP
S
$111,555
3,928
---
4/16/25
---
$28.40
31,926
-11.0
D
R
4/17/25 - 4:53:11 pm
37
    
 
BIRCHLER BRIAN
VP,OO
JB
---
1,875
---
4/15/25
---
---
57,340
3.4
D
R
4/17/25 - 4:53:27 pm
38
    
 
JENNE KYLE
VP
JB
---
12,226
---
4/15/25
---
---
14,215
614.7
D
R
4/17/25 - 4:53:18 pm
39
    
 
BAROLDI JOSEPH
VP
JB
---
10,837
---
4/15/25
---
---
35,854
43.3
D
R
4/17/25 - 4:53:11 pm
40
1y
34
71%
-33%
1
MONIA BRETT P
CEO,DIR
AS
$4,525
140
---
3/11/25
---
$32.32
180,980
-0.1
D
10b
3/13/25 - 4:45:26 pm
41
    
 
SWAYZE ERIC
VP
JB
$11,708
415
---
2/28/25
---
$28.21
48,432
0.9
D
---
3/4/25 - 5:17:02 pm
42
    
 
O NEIL PATRICK R
VP,LO,GC
JB
$15,629
554
---
2/28/25
---
$28.21
56,799
1.0
D
---
3/4/25 - 5:16:55 pm
43
    
 
MONIA BRETT P
CEO,DIR
JB
$12,328
437
---
2/28/25
---
$28.21
181,120
0.2
D
---
3/4/25 - 5:16:51 pm
44
    
 
GEARY RICHARD S
VP
JB
$11,708
415
---
2/28/25
---
$28.21
99,492
0.4
D
---
3/4/25 - 5:16:44 pm
45
    
 
BIRCHLER BRIAN
VP,OO
JB
$11,680
414
---
2/28/25
---
$28.21
55,465
0.8
D
---
3/4/25 - 5:16:33 pm
46
    
 
BENNETT C FRANK
VP
JB
$9,028
320
---
2/28/25
---
$28.21
93,466
0.3
D
---
3/4/25 - 5:16:26 pm
47
1y
39
82%
-58%
1
O NEIL PATRICK R
VP,LO,GC
AS
$39,046
1,207
---
2/20/25
---
$32.35
56,245
-2.1
D
10b
2/24/25 - 4:55:28 pm
48
1y
39
82%
-58%
1
O NEIL PATRICK R
VP,LO,GC
AS
$194,939
6,165
---
2/4/25
---
$31.62
57,452
-9.7
D
10b
2/6/25 - 6:27:25 pm
49
1y
34
71%
-33%
1
MONIA BRETT P
CEO,DIR
AS
$1,229,463
38,843
---
2/4/25
---
$31.65
180,683
-17.7
D
10b
2/6/25 - 6:26:58 pm
50
    
 
SWAYZE ERIC
VP
S
$44,162
1,367
---
1/31/25
---
$32.31
48,017
-2.8
D
R
2/3/25 - 7:27:29 pm
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