<?xml version="1.0" encoding="utf-8"?>
<feed xmlns="http://www.w3.org/2005/Atom">
<title>Legal Insider Trading Data | Free and Professional Subscription Services | Insider Insights</title>
<link href="http://www.insiderinsights.com/news/company/syre" ></link>
<id>urn:uuid:df1efa1b-d5db-9052-e743-3ed53c13b049</id>
<updated>2026-06-24T09:31:28-04:00</updated>
<author>Jonathan Moreland</author>
<subtitle>Profit from legal insider trading. InsiderInsights.com provides free insider trading data tools and resources, and professional grade subscription based real time Form 4 data, analysis and services</subtitle>
<entry>
<title>SYRE: FAIRMOUNT FUNDS MANAGEMENT LLC (DIR) Acquired (JB) 666,680 Shares of SPYRE THERAPEUTICS INC for $0.00 on 6/23</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6431616" ></link>
<id>urn:uuid:231ffd53-328f-d5c0-e890-9d38361b090b</id>
<updated>2026-06-23T21:56:26-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: FAIRMOUNT FUNDS MANAGEMENT LLC (DIR) Disposed (JS) 4.7mm Shares of SPYRE THERAPEUTICS INC for $85.31 on 6/23</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6431617" ></link>
<id>urn:uuid:eaf14ee4-c8b0-8fc3-f389-71fd173c28f6</id>
<updated>2026-06-23T21:56:26-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: HENDERSON MICHAEL THOMAS (DIR) Sold (AS) 20k Shares of SPYRE THERAPEUTICS INC for $100.00 on 6/22</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6431610" ></link>
<id>urn:uuid:de11c6fc-a5ce-d019-fac9-90400dd90564</id>
<updated>2026-06-23T21:32:23-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: SLOAN SHELDON (O) Exercised 8,333 Options (OE) of SPYRE THERAPEUTICS INC for $27.46 on 6/3, and Sold Them All</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6419444" ></link>
<id>urn:uuid:eccf15b4-d141-f3b3-070c-36a8c9d9e337</id>
<updated>2026-06-03T21:32:02-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: TURTLE CAMERON (CEO,DIR) Sold (AS) 15k Shares of SPYRE THERAPEUTICS INC for $69.40-$71.38 on 6/1</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6419440" ></link>
<id>urn:uuid:90a31f50-b13f-5f31-0f35-d6307fc9ce0d</id>
<updated>2026-06-03T21:31:11-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: BURROWS SCOTT L (CFO) Exercised 7,500 Options (OE) of SPYRE THERAPEUTICS INC for $14.50 on 6/1, and Sold Them All</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6419426" ></link>
<id>urn:uuid:b39340c0-6e01-883c-bad0-b9d44f965f46</id>
<updated>2026-06-03T21:30:41-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: HENDERSON MICHAEL THOMAS (DIR) Sold (AS) 80k Shares of SPYRE THERAPEUTICS INC for $72.57-$75.35 on 5/8</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6399253" ></link>
<id>urn:uuid:45153eb0-110d-215f-e6a3-f4a0e713740d</id>
<updated>2026-05-08T21:31:49-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
<entry>
<title>SYRE: BURROWS SCOTT L (CFO) Exercised 12,500 Options (OE) of SPYRE THERAPEUTICS INC for $14.50 on 5/1, and Sold Them All</title>
<link href="http://www.insiderinsights.com/company/syre/spyre-therapeutics-inc/id-6393991" ></link>
<id>urn:uuid:6f29f8f4-38ba-66f4-b755-b7cb4bbeb668</id>
<updated>2026-05-01T21:35:12-04:00</updated>
<summary type="html" ><![CDATA[SPYRE THERAPEUTICS INC (SYRE). Recent Price: $88.34. Mkt Cap:7.7B. 10D Vol: 1.4mm]]></summary>
</entry>
</feed>